F for acute CRP attempts to avoid biasing our data with individuals who are actively experiencing immune responses. However, it is possible that we are including some girls who have slightly elevated CRP and low growth because they have recently been sick. More broadly, it is unclear whether these relatively slight differences in CRP would be measurable in populations with higher rates of inflamma
As an anti-inflammatory effect [51]. How other types of physical activity, such as that associated with agricultural lifestyles, relates to immune function is an important locus for future research. The dominant public health discourse concerning CRP is one of pathology and "chronic inflammation", yet for at least a decade human biologists working in non-Western populations have found lower CRP th
Dipose tissue reserves. In this sample, girls who were growing faster and girls who were depositing lean mass had, on average, lower non-acute CRP. We interpret this as evidence that, in this energy-limited environment, these girls were subsidizing the increased costs of growth in early adolescence through decreasing investment in non-acute immune function. We also find that, regardless of puberta
Y and inflammation [17]. However the inflammation induced by obesity is understood to result from-6 Lower adiposity Higher adiposity-Log CRP -Lower adiposity Higher adiposityBelow median growthAbove median growthFigure 5. Relationships between log CRP, investment in growth and adiposity. Adiposity mediates the relationship between log CRP and growth. Girls who are investing heavily in growth and h
Y and inflammation [17]. However the inflammation induced by obesity is understood to result from-6 Lower adiposity Higher adiposity-Log CRP -Lower adiposity Higher adiposityBelow median growthAbove median growthFigure 5. Relationships between log CRP, investment in growth and adiposity. Adiposity mediates the relationship between log CRP and growth. Girls who are investing heavily in growth and h
Ly transnational world, understanding the significance of immunological biomarkers such as CRP, in both clinical and non-clinical settings, will require integrating knowledge of how different ecological contexts influence the manifestation of non-acute immune function. While working with a subsistence agricultural population of pubertal girls has important benefits for understanding diversity in i
Ly transnational world, understanding the significance of immunological biomarkers such as CRP, in both clinical and non-clinical settings, will require integrating knowledge of how different ecological contexts influence the manifestation of non-acute immune function. While working with a subsistence agricultural population of pubertal girls has important benefits for understanding diversity in i
Urrent caloric excess, but still have very low absolute levels of adipose tissue. While organisms may use markers of energetic balance to judge whether to embark upon long term energetic projects, such as female reproduction [6], an acute immune response will demand a large amount of energy in a short period of time [3]. Given this, it may be more reliable for organisms to use signals of energetic