The observation that 70 of children diagnosed with idiopathic ASD exhibit comorbid medical, developmental or psychiatric conditions [3,6] , including intellectual disability [7] . According to one review, over 100 genes have been linked to syndromic forms of autism [8] . In addition, therepart of10.2217/epi.15.92 ?Dennis R GraysonEpigenomics (2016) 8(1), 85?ISSN 1750-PerspectiveGrayson Guidotti
The observation that 70 of children diagnosed with idiopathic ASD exhibit comorbid medical, developmental or psychiatric conditions [3,6] , including intellectual disability [7] . According to one review, over 100 genes have been linked to syndromic forms of autism [8] . In addition, therepart of10.2217/epi.15.92 ?Dennis R GraysonEpigenomics (2016) 8(1), 85?ISSN 1750-PerspectiveGrayson Guidotti
Ation ?genetics ?prenatal environment ?transcriptomeDennis R Grayson1 Alessandro Guidotti*,1 Department of Psychiatry, The Psychiatric Institute, University of Illinois at Chicago, 1601 W. Taylor St., Chicago, IL 60607, USA *Author for correspondence: Tel.: +1 312 413 4577 dgrayson@ psych.uic.eduThe Center for Disease Control estimates that approximately one in 88 children are diagnosed with aut
Ation ?genetics ?prenatal environment ?transcriptomeDennis R Grayson1 Alessandro Guidotti*,1 Department of Psychiatry, The Psychiatric Institute, University of Illinois at Chicago, 1601 W. Taylor St., Chicago, IL 60607, USA *Author for correspondence: Tel.: +1 312 413 4577 dgrayson@ psych.uic.eduThe Center for Disease Control estimates that approximately one in 88 children are diagnosed with aut
F for acute CRP attempts to avoid biasing our data with individuals who are actively experiencing immune responses. However, it is possible that we are including some girls who have slightly elevated CRP and low growth because they have recently been sick. More broadly, it is unclear whether these relatively slight differences in CRP would be measurable in populations with higher rates of inflamma
Ation ?genetics ?prenatal environment ?transcriptomeDennis R Grayson1 Alessandro Guidotti*,1 Department of Psychiatry, The Psychiatric Institute, University of Illinois at Chicago, 1601 W. Taylor St., Chicago, IL 60607, USA *Author for correspondence: Tel.: +1 312 413 4577 dgrayson@ psych.uic.eduThe Center for Disease Control estimates that approximately one in 88 children are diagnosed with aut
Ation ?genetics ?prenatal environment ?transcriptomeDennis R Grayson1 Alessandro Guidotti*,1 Department of Psychiatry, The Psychiatric Institute, University of Illinois at Chicago, 1601 W. Taylor St., Chicago, IL 60607, USA *Author for correspondence: Tel.: +1 312 413 4577 dgrayson@ psych.uic.eduThe Center for Disease Control estimates that approximately one in 88 children are diagnosed with aut
E MRC/DFID Concordat agreement. Funding to pay the Open Access publication charge for this article was provided by Harvard University. Conflict of interest: None declared.PerspectiveFor reprint orders, please contact: reprints@futuremedicine.comMerging data from genetic and epigenetic approaches to better understand autistic spectrum disorderAutism spectrum disorder (ASD) is a complex neurod