Rioritize the fat deposits critical for reproductive success [39]. While the trade-off between growth and reproduction during the pubertal transition is readily observed and rationalized, attention is rarely directed at investment in maintenance over the same period. Our primary hypothesis here was that maintenance of the immune system might represent a substantial, flexible component of overall e
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
N addition, we thank the two anonymous reviewers for their helpful comments, and the Harvard Institute for Quantitative Social Science for statistical assistance.fundingThis research was supported by a National Science Foundation (NSF) Doctoral Dissertation Improvement Grant (BCS-0925768), an NSF Senior Research Grant (BCS0921237), and an NSF Graduate Research Fellowship for Shattuck-Heidorn. Rese
N addition, we thank the two anonymous reviewers for their helpful comments, and the Harvard Institute for Quantitative Social Science for statistical assistance.fundingThis research was supported by a National Science Foundation (NSF) Doctoral Dissertation Improvement Grant (BCS-0925768), an NSF Senior Research Grant (BCS0921237), and an NSF Graduate Research Fellowship for Shattuck-Heidorn. Rese
It is difficult to parse behavioral from physiological influences without direct measurement of the growth spurt. Alternatively, changes in levels of CRP may signify broader shifts in immunocompetence, perhaps particularly in innate immunocompetence, and not be specific to the action of CRP in particular. Outside of the context of chronic disease and pathology, the functional significance of varia
Ment in other energetic demands, such as reproduction or physical activity, also evidence trade-offs with nonacute immune function? Intriguingly, two recent studies support a hypothesis that there are some trade-offs between female reproductive function and higher levels of CRP. Though they do not| Shattuck-Heidorn et al.Evolution, Medicine, and Public Healthspecifically investigate non-acute CRP,