N addition, we thank the two anonymous reviewers for their helpful comments, and the Harvard Institute for Quantitative Social Science for statistical assistance.fundingThis research was supported by a National Science Foundation (NSF) Doctoral Dissertation Improvement Grant (BCS-0925768), an NSF Senior Research Grant (BCS0921237), and an NSF Graduate Research Fellowship for Shattuck-Heidorn. Rese
N addition, we thank the two anonymous reviewers for their helpful comments, and the Harvard Institute for Quantitative Social Science for statistical assistance.fundingThis research was supported by a National Science Foundation (NSF) Doctoral Dissertation Improvement Grant (BCS-0925768), an NSF Senior Research Grant (BCS0921237), and an NSF Graduate Research Fellowship for Shattuck-Heidorn. Rese
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
Rioritize the fat deposits critical for reproductive success [39]. While the trade-off between growth and reproduction during the pubertal transition is readily observed and rationalized, attention is rarely directed at investment in maintenance over the same period. Our primary hypothesis here was that maintenance of the immune system might represent a substantial, flexible component of overall e
Frequent turnover, requiring some relatively constant commitment of energetic resources, though the metabolic cost of this is unknown. Our data also imply that there are meaningful differences in low levels of CRP. Interestingly, administration of human CRP to mice protects against pneumococcal infections, but not if CRP is administered after exposure to the bacteria, suggesting an early prophylac
Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func