Itive search for orthologues of the 147 S. coelicolor TTA-containing genes (or in some cases gene clusters). We identified 19 that were widespread and frequently TTA-containing in 13 other Streptomyces genomes (Table 2). In addition, a further 10 genes or gene clusters frequently had TTA codons, even though their S. coelicolor orthologues were TTA-free (asterisks in Table 2). As 27/29 of the TTA-c
Factor (AbaA-like) Unknown Unknown SapB biosynthetic enzyme; regulator of SapB biosynthesis Possible phosphotransferase Component of conservon6/13; 7/14 9/11 6/10 8/13 8/12 9/14 8/14 3/11; 5/13 14/14 5/14 12/14 6/14 7/13 5/14 9/14 8/11 12/14 6/14 6/14 7/14 6/13 5/14 5/13 7/14 2/12; 7/12 10/12 9/(? (?(TTA) (? (TTA) (TTA) (??40040 (? 43220 (? ??49090 50850 (TTA) 51100 (TTA) 26520 19600 (? ???16190 3
Factor (AbaA-like) Unknown Unknown SapB biosynthetic enzyme; regulator of SapB biosynthesis Possible phosphotransferase Component of conservon6/13; 7/14 9/11 6/10 8/13 8/12 9/14 8/14 3/11; 5/13 14/14 5/14 12/14 6/14 7/13 5/14 9/14 8/11 12/14 6/14 6/14 7/14 6/13 5/14 5/13 7/14 2/12; 7/12 10/12 9/(? (?(TTA) (? (TTA) (TTA) (??40040 (? 43220 (? ??49090 50850 (TTA) 51100 (TTA) 26520 19600 (? ???16190 3
N each cluster co-evolved (results not shown). WhiJ paralogues in S. coelicolor vary considerably in their conservation in other organisms. One (SCO3421) was present in nearly all complex actinomycetes, and the adjacent gene encoding a likely antisigma factor nearly always contained a TTA codon in Streptomycineae (but in no other groups). Another present in all Streptomycineae (SCO4441) was also w
N each cluster co-evolved (results not shown). WhiJ paralogues in S. coelicolor vary considerably in their conservation in other organisms. One (SCO3421) was present in nearly all complex actinomycetes, and the adjacent gene encoding a likely antisigma factor nearly always contained a TTA codon in Streptomycineae (but in no other groups). Another present in all Streptomycineae (SCO4441) was also w
Tomyces spp: S. coelicolor (Sco), S. pristinaespiralis (Spr), S. griseus (Sgr) and S. venezuelae (Sven). High percentage identity is indicated by the intensity of red, and low identity by the intensity of green. A control table (`Concatenated') shows the comparisons for a concatenated set of seven universal proteins (AtpD, DnaA, DnaG, DnaK, GyrB, RecA, RpoB).2000). The distribution of convincing r
Tomyces spp: S. coelicolor (Sco), S. pristinaespiralis (Spr), S. griseus (Sgr) and S. venezuelae (Sven). High percentage identity is indicated by the intensity of red, and low identity by the intensity of green. A control table (`Concatenated') shows the comparisons for a concatenated set of seven universal proteins (AtpD, DnaA, DnaG, DnaK, GyrB, RecA, RpoB).2000). The distribution of convincing r
Tomyces spp: S. coelicolor (Sco), S. pristinaespiralis (Spr), S. griseus (Sgr) and S. venezuelae (Sven). High percentage identity is indicated by the intensity of red, and low identity by the intensity of green. A control table (`Concatenated') shows the comparisons for a concatenated set of seven universal proteins (AtpD, DnaA, DnaG, DnaK, GyrB, RecA, RpoB).2000). The distribution of convincing r