Y than acquired immunity [47], and may be especially sensitive to energetic indicators. The relationships between adipose tissue, leptin and immune function suggest that organisms increase innate immune vigilance when adipose tissue reserves are sufficient to fund acute immune responses. This framework, of considering the cost of an acute response as underlying the coupling of nonacute immune func
F for acute CRP attempts to avoid biasing our data with individuals who are actively experiencing immune responses. However, it is possible that we are including some girls who have slightly elevated CRP and low growth because they have recently been sick. More broadly, it is unclear whether these relatively slight differences in CRP would be measurable in populations with higher rates of inflamma
F for acute CRP attempts to avoid biasing our data with individuals who are actively experiencing immune responses. However, it is possible that we are including some girls who have slightly elevated CRP and low growth because they have recently been sick. More broadly, it is unclear whether these relatively slight differences in CRP would be measurable in populations with higher rates of inflamma
F for acute CRP attempts to avoid biasing our data with individuals who are actively experiencing immune responses. However, it is possible that we are including some girls who have slightly elevated CRP and low growth because they have recently been sick. More broadly, it is unclear whether these relatively slight differences in CRP would be measurable in populations with higher rates of inflamma
Y and inflammation [17]. However the inflammation induced by obesity is understood to result from-6 Lower adiposity Higher adiposity-Log CRP -Lower adiposity Higher adiposityBelow median growthAbove median growthFigure 5. Relationships between log CRP, investment in growth and adiposity. Adiposity mediates the relationship between log CRP and growth. Girls who are investing heavily in growth and h
As an anti-inflammatory effect [51]. How other types of physical activity, such as that associated with agricultural lifestyles, relates to immune function is an important locus for future research. The dominant public health discourse concerning CRP is one of pathology and "chronic inflammation", yet for at least a decade human biologists working in non-Western populations have found lower CRP th
As an anti-inflammatory effect [51]. How other types of physical activity, such as that associated with agricultural lifestyles, relates to immune function is an important locus for future research. The dominant public health discourse concerning CRP is one of pathology and "chronic inflammation", yet for at least a decade human biologists working in non-Western populations have found lower CRP th
Egulates energy metabolism and storage and is also the site of immune and antibacterial responses [41, 42]. And it is well-known that a minimum level of body fat and the hormone leptin is necessary to maintain T-mediated immunity [43], and that leptin can regulate inflammatory immune processes, including stimulating Il-6 production in macrophages [44, 45]. This is congruent with our initial eviden