The observation that 70 of children diagnosed with idiopathic ASD exhibit comorbid medical, developmental or psychiatric conditions [3,6] , including intellectual disability [7] . According to one review, over 100 genes have been linked to syndromic forms of autism [8] . In addition, therepart of10.2217/epi.15.92 ?Dennis R GraysonEpigenomics (2016) 8(1), 85?ISSN 1750-PerspectiveGrayson Guidotti