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We in addition acquired mutant rats which in fact had both Pax6 gene mutation and the small-eye phenotype. Using this heterozygous Pax6 mutant mouse model, all of us even more looked at what sort of Pax6 gene mutation brought on excessive carbs and glucose metabolism in these mice and probably inside the man aniridia sufferers, as well. Methods Participants: id of a pedigree using the PAX6 gene mu